Pyrethroids in an AlphaFold2 Model of the Insect Sodium Channel

Pyrethroid insecticides stabilize the open state of insect sodium channels. Previous mutational, electrophysiological, and computational analyses led to the development of homology models predicting two pyrethroid receptor sites, PyR1 and PyR2. Many of the naturally occurring sodium channel mutation...

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Bibliographic Details
Main Authors: Boris S. Zhorov, Ke Dong
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Insects
Subjects:
Online Access:https://www.mdpi.com/2075-4450/13/8/745