A bioactive injectable self-healing anti-inflammatory hydrogel with ultralong extracellular vesicles release synergistically enhances motor functional recovery of spinal cord injury

A bioactive injectable self-healing anti-inflammatory hydrogel with ultralong extracellular vesicles release synergistically enhances motor functional recovery of spinal cord injury

The repair and motor functional recovery after spinal cord injury (SCI) remains a worldwide challenge. The inflammatory microenvironment is one of main obstacles on inhibiting the recovery of SCI. Using mesenchymal stem cells (MSCs) derived extracellular vesicles to replace MSCs transplantation and...

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Bibliographic Details
Main Authors: Chenggui Wang, Min Wang, Kaishun Xia, Jingkai Wang, Feng Cheng, Kesi Shi, Liwei Ying, Chao Yu, Haibin Xu, Shining Xiao, Chengzhen Liang, Fangcai Li, Bo Lei, Qixin Chen
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2021-08-01
Series:Bioactive Materials
Subjects:
Bioactive biomaterials
Multifunctional hydrogel
Extracellular vesicles release
Spinal cord injury repair
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X21000414

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http://www.sciencedirect.com/science/article/pii/S2452199X21000414

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