Real-time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin-binding proteins
Peptidoglycan is an essential component of the bacterial cell envelope that surrounds the cytoplasmic membrane to protect the cell from osmotic lysis. Important antibiotics such as β-lactams and glycopeptides target peptidoglycan biosynthesis. Class A penicillin-binding proteins (PBPs) are bifunctio...
Principais autores: | , , , , , |
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Formato: | Artigo |
Idioma: | English |
Publicado em: |
eLife Sciences Publications Ltd
2021-02-01
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coleção: | eLife |
Assuntos: | |
Acesso em linha: | https://elifesciences.org/articles/61525 |