Real-time monitoring of peptidoglycan synthesis by membrane-reconstituted penicillin-binding proteins

Peptidoglycan is an essential component of the bacterial cell envelope that surrounds the cytoplasmic membrane to protect the cell from osmotic lysis. Important antibiotics such as β-lactams and glycopeptides target peptidoglycan biosynthesis. Class A penicillin-binding proteins (PBPs) are bifunctio...

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Detalhes bibliográficos
Principais autores: Víctor M Hernández-Rocamora, Natalia Baranova, Katharina Peters, Eefjan Breukink, Martin Loose, Waldemar Vollmer
Formato: Artigo
Idioma:English
Publicado em: eLife Sciences Publications Ltd 2021-02-01
coleção:eLife
Assuntos:
Acesso em linha:https://elifesciences.org/articles/61525