The trajectory of intrahelical lesion recognition and extrusion by the human 8-oxoguanine DNA glycosylase
DNA glycosylases are lesion-specific enzymes that recognize specific nucleobase damages and catalyze their excision through cleavage of the glycosidic bond. Here, the authors present the crystal structures of human 8-oxoguanine (oxoG) DNA glycosylase bound to undamaged DNA and to DNA containing an i...
| Autors principals: | , , , , , , |
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| Format: | Article |
| Idioma: | English |
| Publicat: |
Nature Portfolio
2020-09-01
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| Col·lecció: | Nature Communications |
| Accés en línia: | https://doi.org/10.1038/s41467-020-18290-2 |