Attenuation of Methotrexate-Induced Embryotoxicity and Oxidative Stress by Ethyl Pyruvate
Background Methotrexate (MTX), as an anti-folate agent, is widely used in the treatment of rheumatic disorders and malignant tumors, however it damages reproductive sys- tem in mice. The aim of this research was to study the effects of ethyl pyruvate (EP) on embryo development and oxidative stress c...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Royan Institute (ACECR), Tehran
2016-07-01
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Series: | International Journal of Fertility and Sterility |
Subjects: | |
Online Access: | http://www.ijfs.ir/article_45383_1dd4fc5c8f1c5c58f6cf7171b5f0824c.pdf |