Attenuation of Methotrexate-Induced Embryotoxicity and Oxidative Stress by Ethyl Pyruvate

Background Methotrexate (MTX), as an anti-folate agent, is widely used in the treatment of rheumatic disorders and malignant tumors, however it damages reproductive sys- tem in mice. The aim of this research was to study the effects of ethyl pyruvate (EP) on embryo development and oxidative stress c...

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Bibliographic Details
Main Authors: Gholamreza Najafi, Elham Atashfaraz, Farah Farokhi
Format: Article
Language:English
Published: Royan Institute (ACECR), Tehran 2016-07-01
Series:International Journal of Fertility and Sterility
Subjects:
Online Access:http://www.ijfs.ir/article_45383_1dd4fc5c8f1c5c58f6cf7171b5f0824c.pdf