The Phosphodiesterase 4 Inhibitor Prevents Antigen-induced Biphasic Nasal Obstruction in Brown Norway Rats

Background: Nasal obstruction is considered the most serious problem for patients with allergic rhinitis. We have previously established a model of nasal obstruction in guinea pigs. In the present study, we tried to establish an allergic model of nasal obstruction using Brown Norway (BN) rats to eva...

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Bibliographic Details
Main Authors: Hirokazu Kawasaki, Toshihiko Kaise, Haruhiko Manabe, Akihiko Watanabe
Format: Article
Language:English
Published: Elsevier 2005-01-01
Series:Allergology International
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1323893015310558