FKBP51, AmotL2 and IQGAP1 Involvement in Cilastatin Prevention of Cisplatin-Induced Tubular Nephrotoxicity in Rats

The immunophilin FKBP51, the angiomotin AmotL2, and the scaffoldin IQGAP1 are overexpressed in many types of cancer, with the highest increase in leucocytes from patients undergoing oxaliplatin chemotherapy. Inflammation is involved in the pathogenesis of nephrotoxicity induced by platinum analogs....

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Bibliographic Details
Main Authors: Rebeca González-Fernández, María Ángeles González-Nicolás, Manuel Morales, Julio Ávila, Alberto Lázaro, Pablo Martín-Vasallo
Format: Article
Language:English
Published: MDPI AG 2022-05-01
Series:Cells
Subjects:
Online Access:https://www.mdpi.com/2073-4409/11/9/1585