Human fetal skin derived merkel cells display distinctive characteristics in vitro and in bio-engineered skin substitutes in vivo

Human fetal skin derived merkel cells display distinctive characteristics in vitro and in bio-engineered skin substitutes in vivo

Human skin contains specialized neuroendocrine Merkel cells responsible for fine touch sensation. In the present study, we performed in-depth analysis of Merkel cells in human fetal back skin. We revealed that these Merkel cells expressed cytokeratin 20 (CK20), were positive for the neuroendocrine m...

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Bibliographic Details
Main Authors: Katarzyna Michalak-Micka, Dominic Rütsche, Luca Mazzone, Vanessa L. Büchler, Ueli Moehrlen, Agnes S. Klar, Thomas Biedermann
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-09-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
human fetal skin
Merkel cell
CK20
skin substitute
skin tissue engineering
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2022.983870/full

Internet

https://www.frontiersin.org/articles/10.3389/fbioe.2022.983870/full

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