Modulation of protease activated receptor 1 influences human metapneumovirus disease severity in a mouse model.

Human metapneumovirus (hMPV) infection causes acute respiratory tract infections (RTI) which can result in hospitalization of both children and adults. To date, no antiviral or vaccine is available for this common viral infection. Immunomodulators could represent an interesting strategy for the trea...

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Bibliographic Details
Main Authors: Laetitia Aerts, Marie-Ève Hamelin, Chantal Rhéaume, Sophie Lavigne, Christian Couture, Woojin Kim, Delia Susan-Resiga, Annik Prat, Nabil G Seidah, Nathalie Vergnolle, Beatrice Riteau, Guy Boivin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3755973?pdf=render