Neurogenetic mechanisms of risk for ADHD: Examining associations of polygenic scores and brain volumes in a population cohort

Neurogenetic mechanisms of risk for ADHD: Examining associations of polygenic scores and brain volumes in a population cohort

Abstract Background ADHD polygenic scores (PGSs) have been previously shown to predict ADHD outcomes in several studies. However, ADHD PGSs are typically correlated with ADHD but not necessarily reflective of causal mechanisms. More research is needed to elucidate the neurobiological mechanisms unde...

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Bibliographic Details
Main Authors: Quanfa He, Taylor J. Keding, Qi Zhang, Jiacheng Miao, Justin D. Russell, Ryan J. Herringa, Qiongshi Lu, Brittany G. Travers, James J. Li
Format: Article
Language:English
Published: BMC 2023-08-01
Series:Journal of Neurodevelopmental Disorders
Subjects:
ADHD
Polygenic scores
Brain volume
Functional annotation
Multiple mediation
Online Access:https://doi.org/10.1186/s11689-023-09498-6

Internet

https://doi.org/10.1186/s11689-023-09498-6

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