Relaxin inhibits 177Lu-EDTMP associated cell death in osteosarcoma cells through notch-1 pathway

Relaxin inhibits 177Lu-EDTMP associated cell death in osteosarcoma cells through notch-1 pathway

177Lu-EDTMP (Ethylenediamine tetramethylene phosphonic acid) is the most used radioactive agent for pain palliation in bone cancer patients. The present study aims to study the impact of relaxin-2 on the 177Lu-EDTMP associated cell toxicity and death in osteosarcoma cells. MG63 and Saos-2 cells were...

Full description

Bibliographic Details
Main Authors: Xu Junhua, Wan Song, Chen Wei, Zhang Yi, Ji Zhenzhong
Format: Article
Language:English
Published: Sciendo 2022-12-01
Series:Acta Pharmaceutica
Subjects:
osteosarcoma
relaxin-2
cell death
apoptosis
notch-1 pathway
Online Access:https://doi.org/10.2478/acph-2022-0032

Internet

https://doi.org/10.2478/acph-2022-0032

Similar Items