Role and significance of SIRT1 in regulating the LPS-activated pyroptosis pathway in children with congenital hydronephrosis

Objective To explore the characteristics and mechanism of sirtuin 1 (SIRT1) in lipopolysaccharide (LPS)-activated pyroptosis in the renal tissue of children with congenital hydronephrosis (CHn).Methods We detected the expression characteristics and clinical significance of SIRT1 and pyroptosis pathw...

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Bibliographic Details
Main Authors: Juan Zhou, Daxing Tang, Zhan Wang, Gu Weizhong
Format: Article
Language:English
Published: BMJ Publishing Group 2023-10-01
Series:World Journal of Pediatric Surgery
Online Access:https://wjps.bmj.com/content/6/4/e000602.full