Influence of Bioluminescence Imaging Dynamics by D-Luciferin Uptake and Efflux Mechanisms

Bioluminescence imaging (BLI) detects light generated by luciferase-mediated oxidation of substrate and is used widely for evaluating transgene expression in cell-based assays and in vivo in relevant preclinical models. The most commonly used luciferase for in vivo applications is firefly luciferase...

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Bibliographic Details
Main Authors: Yimao Zhang, Mrudula Pullambhatla, John Laterra, Martin G. Pomper
Format: Article
Language:English
Published: SAGE Publications 2012-11-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2012.00005