Comprehensive survey of conserved RNA secondary structures in full-genome alignment of Hepatitis C virus

Abstract Hepatitis C virus (HCV) is a plus-stranded RNA virus that often chronically infects liver hepatocytes and causes liver cirrhosis and cancer. These viruses replicate their genomes employing error-prone replicases. Thereby, they routinely generate a large ‘cloud’ of RNA genomes (quasispecies)...

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Bibliographic Details
Main Authors: Sandra Triebel, Kevin Lamkiewicz, Nancy Ontiveros, Blake Sweeney, Peter F. Stadler, Anton I. Petrov, Michael Niepmann, Manja Marz
Format: Article
Language:English
Published: Nature Portfolio 2024-07-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-024-62897-0