Galantamine ameliorates hyperoxia-induced brain injury in neonatal mice

Galantamine ameliorates hyperoxia-induced brain injury in neonatal mice

Introduction:Prolonged oxygen therapy in preterm infants often leads to cognitive impairment. Hyperoxia leads to excess free radical production with subsequent neuroinflammation, astrogliosis, microgliosis and apoptosis. We hypothesized that Galantamine, an acetyl choline esterase inhibitor and an F...

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Bibliographic Details
Main Authors: Nahla Zaghloul, Naomi S. Cohen, Kamesh R. Ayasolla, Hsiu-Ling Li, Dalibor Kurepa, Mohamed N. Ahmed
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-06-01
Series:Frontiers in Neuroscience
Subjects:
hyperoxia induced brain injury
galantamine
acetylcholine esterase inhibitor
neuroinflammation
reactive oxygen species
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2023.890015/full

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https://www.frontiersin.org/articles/10.3389/fnins.2023.890015/full

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