Review of Shikonin and Derivatives: Isolation, Chemistry, Biosynthesis, Pharmacology and Toxicology

Shikonin and its derivatives, isolated from traditional medicinal plant species of the genus Lithospermum, Alkanna, Arnebia, Anchusa, Onosma, and Echium belonging to the Boraginaceae family, have numerous applications in foods, cosmetics, and textiles. Shikonin, a potent bioactive red pigment, has b...

Full description

Bibliographic Details
Main Authors: Snehlata Yadav, Ajay Sharma, Gulzar Ahmad Nayik, Raymond Cooper, Garima Bhardwaj, Harvinder Singh Sohal, Vishal Mutreja, Ramandeep Kaur, Franklin Ore Areche, Mohannad AlOudat, Ayaz Mukarram Shaikh, Béla Kovács, Abdelhakam Esmaeil Mohamed Ahmed
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.905755/full