Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and motor impairments in an experimental model of chronic traumatic brain injury.

Combination therapy of human umbilical cord blood cells and granulocyte colony stimulating factor reduces histopathological and motor impairments in an experimental model of chronic traumatic brain injury.

Traumatic brain injury (TBI) is associated with neuro-inflammation, debilitating sensory-motor deficits, and learning and memory impairments. Cell-based therapies are currently being investigated in treating neurotrauma due to their ability to secrete neurotrophic factors and anti-inflammatory cytok...

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Bibliographic Details
Main Authors: Sandra A Acosta, Naoki Tajiri, Kazutaka Shinozuka, Hiroto Ishikawa, Paul R Sanberg, Juan Sanchez-Ramos, Shijie Song, Yuji Kaneko, Cesar V Borlongan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3951247?pdf=render

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http://europepmc.org/articles/PMC3951247?pdf=render

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