Imaging single-channel calcium microdomains by total internal reflection microscopy
The microdomains of Ca2+ in the cytosol around the mouth of open Ca2+ channels are the basic `building blocks' from which cellular Ca2+ signals are constructed. Moreover, the kinetics of local [Ca2+] closely reflect channel gating, so their measurement holds promise as an alternative to electro...
Main Authors: | ANGELO DEMURO, IAN PARKER |
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Format: | Article |
Language: | English |
Published: |
BMC
2004-01-01
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Series: | Biological Research |
Subjects: | |
Online Access: | http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000400025 |
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