Chromosomal Translocations Detection in Cancer Cells Using Chromosomal Conformation Capture Data

Chromosomal Translocations Detection in Cancer Cells Using Chromosomal Conformation Capture Data

Complex chromosomal rearrangements such as translocations play a critical role in oncogenesis. Translocation detection is vital to decipher their biological role in activating cancer-associated mechanisms. High-throughput chromosomal conformations capture (Hi-C) data have shown promising progress in...

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Bibliographic Details
Main Authors: Muhammad Muzammal Adeel, Khaista Rehman, Yan Zhang, Yibeltal Arega, Guoliang Li
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Genes
Subjects:
3D-genome
translocations detection
cancers
WGS
PCR
Hi-C
Online Access:https://www.mdpi.com/2073-4425/13/7/1170

Internet

https://www.mdpi.com/2073-4425/13/7/1170

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