p53 gene analysis in childhood B non - Hodgkin's lymphoma

CONTEXT: Mutations or deletions in the tumor-suppressor gene p53 are among the commonest genetic changes found in human neoplasms including breast, lung and bowel cancers. In hematological malignancies, p53 is most often mutated in Burkitt's lymphoma, with p53 mutations present in 30 to 40% of...

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Bibliographic Details
Main Authors: Claudete Esteves Nogueira Pinto Klumb, Lídia Maria Magalhães de Resende, Eloísa Helena Tajara, Erika Cristina Pavarino Bertelli, Vivian Mary Rumjanek, Raquel Ciuvalschi Maia
Format: Article
Language:English
Published: Associação Paulista de Medicina
Series:São Paulo Medical Journal
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-31802001000600006&lng=en&tlng=en