Sulforaphane attenuates platelet granule secretion through down-regulating glycoprotein VI-mediated p38 MAPK/cPLA2 signaling pathway

Sulforaphane attenuates platelet granule secretion through down-regulating glycoprotein VI-mediated p38 MAPK/cPLA2 signaling pathway

ABSTRACTGlycoprotein VI (GPVI) is the major collagen receptor on the platelet surface and is important in mediating granule secretion and atherothrombosis. Sulforaphane (SFN), a dietary isothiocyanate enriched in cruciferous vegetables, exerts multiple biological activities. This study aimed to inve...

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Bibliographic Details
Main Authors: Xinhui Huang, Xinyu Zhou, Chunting Wu, Weiqi Li, Yongjie Ma, Qilian He, Fuli Ya
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:CyTA - Journal of Food
Subjects:
Sulforaphane
glycoprotein VI
platelet granule
P38 MAPK
cytosolic phospholipase A2
thromboxane A2
Online Access:https://www.tandfonline.com/doi/10.1080/19476337.2023.2173307

Internet

https://www.tandfonline.com/doi/10.1080/19476337.2023.2173307

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