A spider-derived Kunitz-type serine protease inhibitor that acts as a plasmin inhibitor and an elastase inhibitor.

Kunitz-type serine protease inhibitors are involved in various physiological processes, such as ion channel blocking, blood coagulation, fibrinolysis, and inflammation. While spider-derived Kunitz-type proteins show activity in trypsin or chymotrypsin inhibition and K(+) channel blocking, no additio...

Full description

Bibliographic Details
Main Authors: Hu Wan, Kwang Sik Lee, Bo Yeon Kim, Feng Ming Zou, Hyung Joo Yoon, Yeon Ho Je, Jianhong Li, Byung Rae Jin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3537671?pdf=render