Stabilization of PIM Kinases in Hypoxia Is Mediated by the Deubiquitinase USP28

Proviral integration sites for Moloney murine leukemia virus (PIM) kinases are upregulated at the protein level in response to hypoxia and have multiple protumorigenic functions, promoting cell growth, survival, and angiogenesis. However, the mechanism responsible for the induction of PIM in hypoxia...

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书目详细资料
Main Authors: Rachel K. Toth, Regina Solomon, Noel A. Warfel
格式: 文件
语言:English
出版: MDPI AG 2022-03-01
丛编:Cells
主题:
在线阅读:https://www.mdpi.com/2073-4409/11/6/1006