CYP 450 2C19 polymorphisms in Indian patients with coronary artery disease

Background: Dual antiplatelet therapy is the cornerstone in the management of acute coronary syndromes (ACS) and prevention of stent thrombosis (ST). Genetic polymorphisms in CYP2C19 gene involved in hepatic activation of clopidogrel leads to clopidogrel non-responsiveness and may influence clinical...

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Bibliographic Details
Main Authors: Sudhir S. Shetkar, Sivasubramanian Ramakrishnan, Sandeep Seth, Puneet Chandna, Sunil K. Verma, Balram Bhargava, Vinay K. Bahl
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Indian Heart Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0019483213003209