A rationally enhanced red fluorescent protein expands the utility of FRET biosensors

Abstract Genetically encoded Förster Resonance Energy Transfer (FRET)-based biosensors are powerful tools to illuminate spatiotemporal regulation of cell signaling in living cells, but the utility of the red spectrum for biosensing was limited due to a lack of bright and stable red fluorescent prote...

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Bibliographic Details
Main Authors: Gary C. H. Mo, Clara Posner, Erik A. Rodriguez, Tengqian Sun, Jin Zhang
Format: Article
Language:English
Published: Nature Portfolio 2020-04-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-15687-x