MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer
Abstract Many immune suppressive mechanisms utilized by triple negative breast cancer (TNBC) are regulated by oncogenic epithelial-to-mesenchymal transition (EMT). How TNBC EMT impacts innate immune cells is not fully understood. To determine how TNBC suppresses antitumor macrophages, we used microR...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-05-01
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Series: | npj Breast Cancer |
Online Access: | https://doi.org/10.1038/s41523-021-00273-1 |