Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance

Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance

Summary: Bladder cancer (BLCA) is more common in men but more aggressive in women. Sex-based differences in cancer biology are commonly studied using a murine model with BLCA generated by N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN). While tumors in the BBN model have been profiled, these profiles p...

Full description

Bibliographic Details
Main Authors: Hany A. Abdel-Hafiz, Saravana Kumar Kailasam Mani, Wesley Huang, Kenneth H. Gouin, III, Yuzhou Chang, Tong Xiao, Qin Ma, Zihai Li, Simon R.V. Knott, Dan Theodorescu
Format: Article
Language:English
Published: Elsevier 2023-09-01
Series:iScience
Subjects:
Cancer
Cancer systems biology
Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004223017807

Internet

http://www.sciencedirect.com/science/article/pii/S2589004223017807

Similar Items