Single-cell profiling of murine bladder cancer identifies sex-specific transcriptional signatures with prognostic relevance
Summary: Bladder cancer (BLCA) is more common in men but more aggressive in women. Sex-based differences in cancer biology are commonly studied using a murine model with BLCA generated by N-butyl-N-(4-hydroxybutyl)-nitrosamine (BBN). While tumors in the BBN model have been profiled, these profiles p...
Main Authors: | Hany A. Abdel-Hafiz, Saravana Kumar Kailasam Mani, Wesley Huang, Kenneth H. Gouin, III, Yuzhou Chang, Tong Xiao, Qin Ma, Zihai Li, Simon R.V. Knott, Dan Theodorescu |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2023-09-01
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Series: | iScience |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2589004223017807 |
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