A candidate glycoconjugate vaccine induces protective antibodies in the serum and intestinal secretions, antibody recall response and memory T cells and protects against both typhoidal and non-typhoidal Salmonella serovars

A candidate glycoconjugate vaccine induces protective antibodies in the serum and intestinal secretions, antibody recall response and memory T cells and protects against both typhoidal and non-typhoidal Salmonella serovars

Human Salmonella infections pose significant public health challenges globally, primarily due to low diagnostic yield of systemic infections, emerging and expanding antibiotic resistance of both the typhoidal and non-typhoidal Salmonella strains and the development of asymptomatic carrier state that...

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Bibliographic Details
Main Authors: Risha Haldar, Amlanjyoti Dhar, Debayan Ganguli, Suparna Chakraborty, Ananda Pal, George Banik, Shin-ichi Miyoshi, Santasabuj Das
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Immunology
Subjects:
glycoconjugate vaccine
O-specific polysaccharide (OSP)
typhoidal and non-typhoidal Salmonella serovars
secretory IgA (sIgA)
serum bactericidal assay (SBA)
soft agar motility inhibition assay
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1304170/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1304170/full

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