Compromised Blood-Brain Barrier Junctions Enhance Melanoma Cell Intercalation and Extravasation

Compromised Blood-Brain Barrier Junctions Enhance Melanoma Cell Intercalation and Extravasation

Melanoma frequently metastasises to the brain, and a detailed understanding of the molecular and cellular mechanisms underlying melanoma cell extravasation across the blood-brain barrier (BBB) is important for preventing brain metastasis formation. Making use of primary mouse brain microvascular end...

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Bibliographic Details
Main Authors: Federico Saltarin, Adrian Wegmüller, Leire Bejarano, Ece Su Ildiz, Pascale Zwicky, Andréj Vianin, Florentin Spadin, Klara Soukup, Vladimir Wischnewski, Britta Engelhardt, Urban Deutsch, Ines J. Marques, Martin Frenz, Johanna A. Joyce, Ruth Lyck
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Cancers
Subjects:
melanoma
metastasis
cell extravasation
blood-brain barrier (BBB)
endothelial junctions
Online Access:https://www.mdpi.com/2072-6694/15/20/5071

Internet

https://www.mdpi.com/2072-6694/15/20/5071

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