Glucose fluctuations aggravate myocardial fibrosis via activating the CaMKII/Stat3 signaling in type 2 diabtetes

Glucose fluctuations aggravate myocardial fibrosis via activating the CaMKII/Stat3 signaling in type 2 diabtetes

Abstract Background Glucose fluctuations (GF) are a risk factor for cardiovascular complications associated with type 2 diabetes. However, there is a lack of adequate research on the effect of GF on myocardial fibrosis and the underlying mechanisms in type 2 diabetes. This study aimed to investigate...

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Bibliographic Details
Main Authors: Lei Zhang, Huan-Huan Liu, Fan Yang, Zhi-Yuan Zhang, Zhen-Ye Zhang, Xiao-Xi Zhao, Ling-Ling Qian, Shi-Peng Dang, Ru-Xing Wang
Format: Article
Language:English
Published: BMC 2023-10-01
Series:Diabetology & Metabolic Syndrome
Subjects:
Glucose fluctuations
Myocardial fibrosis
CaMKII
Stat3
Online Access:https://doi.org/10.1186/s13098-023-01197-5

Internet

https://doi.org/10.1186/s13098-023-01197-5

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