Sirt1 coordinates with ERα to regulate autophagy and adiposity
Abstract Sex difference in adiposity has long been recognized but the mechanism remains incompletely understood. Previous studies suggested that adiposity was regulated by autophagy in response to energy status change. Here, we show that the energy sensor Sirt1 mediates sex difference in adiposity b...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2021-03-01
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Series: | Cell Death Discovery |
Online Access: | https://doi.org/10.1038/s41420-021-00438-8 |