Spontaneous Cell Competition in Immortalized Mammalian Cell Lines.

Cell competition is a form of cell-cell interaction by which cells compare relative levels of fitness, resulting in the active elimination of less-fit cells, "losers," by more-fit cells, "winners." Here, we show that in three routinely-used mammalian cell lines - U2OS, 3T3, and M...

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Bibliographic Details
Main Authors: Alfredo I Penzo-Méndez, Yi-Ju Chen, Jinyang Li, Eric S Witze, Ben Z Stanger
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4511643?pdf=render