Optimized conditions for gene transduction into primary immune cells using viral vectors
Abstract Chimeric antigen receptor (CAR) T cell therapy has emerged as a promising modality for anti-cancer treatment. Its efficacy is quite remarkable in hematological tumors. Owing to their excellent clinical results, gene- modified cell therapies, including T cells, natural killer (NK) cells, and...
Main Authors: | Yeongrin Kim, Da Yeon Lee, Ji U Choi, Jin Song Park, So Myoung Lee, Chung Hyo Kang, Chi Hoon Park |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-07-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-39597-2 |
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