Synergistic Effect of Toceranib and Nanohydroxyapatite as a Drug Delivery Platform—Physicochemical Properties and In Vitro Studies on Mastocytoma Cells

Synergistic Effect of Toceranib and Nanohydroxyapatite as a Drug Delivery Platform—Physicochemical Properties and In Vitro Studies on Mastocytoma Cells

A new combination of Toceranib (Toc; 5-[(5Z)-(5-Fluoro-2-oxo-1,2-dihydro-3H-indol-3-ylidene)methyl]-2,4-dimethyl-<i>N</i>-[2-(pyrrolidin-1-yl)ethyl]-1H-pyrrole-3-carboxamide) with nanohydroxyapatite (nHAp) was proposed as an antineoplastic drug delivery system. Its physicochemical proper...

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Bibliographic Details
Main Authors: Paulina Sobierajska, Anna Serwotka-Suszczak, Sara Targonska, Damian Szymanski, Krzysztof Marycz, Rafal J. Wiglusz
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:International Journal of Molecular Sciences
Subjects:
nanocarriers
hydroxyapatite
surface properties
targeted release
anticancer drug
mast cell tumour
Online Access:https://www.mdpi.com/1422-0067/23/4/1944

Internet

https://www.mdpi.com/1422-0067/23/4/1944

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