Annexin A5 Binds to Lipopolysaccharide and Reduces Its Endotoxin Activity

ABSTRACT Annexin A5 (AnxA5) has a high affinity for phosphatidylserine. The protein is widely used to detect apoptotic cells because phosphatidylserine, a phospholipid that is normally present in the inner leaflets of cytoplasmic membranes, becomes translocated to the outer leaflets during programme...

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Bibliographic Details
Main Authors: Jacob H. Rand, Xiao-Xuan Wu, Elaine Y. Lin, Alexander Griffel, Philip Gialanella, John C. McKitrick
Format: Article
Language:English
Published: American Society for Microbiology 2012-05-01
Series:mBio
Online Access:https://journals.asm.org/doi/10.1128/mBio.00292-11