PRMT4-mediated arginine methylation promotes tyrosine phosphorylation of VEGFR-2 and regulates filopodia protrusions

PRMT4-mediated arginine methylation promotes tyrosine phosphorylation of VEGFR-2 and regulates filopodia protrusions

Summary: Through tightly controlled multilayer mechanisms, vascular endothelial growth factor receptor-2 (VEGFR-2) activation and its downstream signal transduction govern vasculogenesis and pathological angiogenesis, such as tumor angiogenesis. Therefore, it is critical to understand the molecular...

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Bibliographic Details
Main Authors: Edward Hartsough, Rajani R.J. Shelke, Razie Amraei, Zahra Aryan, Saran Lotfollahzadeh, Nader Rahimi
Format: Article
Language:English
Published: Elsevier 2022-08-01
Series:iScience
Subjects:
Biochemistry
Molecular physiology
Cell biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004222010082

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http://www.sciencedirect.com/science/article/pii/S2589004222010082

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