Effects of adipocyte-specific Dkk1 deletion on bone homeostasis and obesity-induced bone loss in male mice

The link between obesity and low bone strength has become a significant medical concern. The canonical Wnt signaling pathway is a key regulator of mesenchymal stem cell differentiation into either osteoblasts or adipocytes with active Wnt signaling promoting osteoblastogenesis. Our previous research...

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Bibliographic Details
Main Authors: Souad Daamouch, Sylvia Thiele, Lorenz Hofbauer, Martina Rauner
Format: Article
Language:English
Published: Bioscientifica 2023-10-01
Series:Endocrine Connections
Subjects:
Online Access:https://ec.bioscientifica.com/view/journals/ec/12/11/EC-23-0251.xml