Pubertal lead exposure affects ovary development, folliculogenesis and steroidogenesis by activation of IRE1α-JNK signaling pathway in rat

Epidemic studies showed that lead exposures are associated with various female reproductive dysfunctions, including infertility, miscarriage, preterm delivery, and early menopause. However, the mechanism involved is still unclear. In the current study, SD rats were exposed to lead at doses of 0, 5,...

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Bibliographic Details
Main Authors: Dan Shan, Xin Wen, Xiaoju Guan, Hangping Fang, Yijia Liu, Mengjie Qin, Hu Wang, Jingfeng Xu, Jieqiang Lv, Junzhao Zhao, Haolin Chen
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651323004232