Design, Synthesis, Evaluation and Molecular Dynamics Simulation of Dengue Virus NS5-RdRp Inhibitors

Dengue virus (DENV) is a major mosquito-borne human pathogen in tropical countries; however, there are currently no targeted antiviral treatments for DENV infection. Compounds <b>27</b> and <b>29</b> have been reported to be allosteric inhibitors of DENV RdRp with potent inhi...

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Bibliographic Details
Main Authors: Keli Zong, Wei Li, Yijie Xu, Xu Zhao, Ruiyuan Cao, Hong Yan, Xingzhou Li
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/16/11/1625