FLARE: a fast and flexible workflow for identifying RNA editing foci

Abstract Background Fusion of RNA-binding proteins (RBPs) to RNA base-editing enzymes (such as APOBEC1 or ADAR) has emerged as a powerful tool for the discovery of RBP binding sites. However, current methods that analyze sequencing data from RNA-base editing experiments are vulnerable to false posit...

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Bibliographic Details
Main Authors: Eric Kofman, Brian Yee, Hugo C. Medina-Munoz, Gene W. Yeo
Format: Article
Language:English
Published: BMC 2023-10-01
Series:BMC Bioinformatics
Subjects:
Online Access:https://doi.org/10.1186/s12859-023-05452-4