Diet-induced obese mice are resistant to improvements in cardiac function resulting from short-term adropin treatment

Diet-induced obese mice are resistant to improvements in cardiac function resulting from short-term adropin treatment

Previous studies have shown that treatment with recombinant adropin, a circulating peptide secreted by the liver and brain, restores glucose utilization in the hearts of diet-induced obese mice. This restoration of fuel substrate flexibility, which is lost in obese and diabetic animals, has the pote...

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Bibliographic Details
Main Authors: Dharendra Thapa, Bingxian Xie, Bellina A.S. Mushala, Manling Zhang, Janet R. Manning, Paramesha Bugga, Michael W. Stoner, Michael J. Jurczak, Iain Scott
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Current Research in Physiology
Subjects:
Adropin
Cardiac function
High fat diet
Mice
Contractility
Insulin
Online Access:http://www.sciencedirect.com/science/article/pii/S2665944122000050

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http://www.sciencedirect.com/science/article/pii/S2665944122000050

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