PPARG is a potential target of Tanshinone IIA in prostate cancer treatment: a combination study of molecular docking and dynamic simulation based on transcriptomic bioinformatics

PPARG is a potential target of Tanshinone IIA in prostate cancer treatment: a combination study of molecular docking and dynamic simulation based on transcriptomic bioinformatics

Abstract Tanshinone IIA is a lipophilic organic compound from the root of Danshen (Salvia miltiorrhiza) and is one of the most well-known Tanshinone molecules by pharmacologists. In recent years, in addition to effects of anti-cardiovascular and neurological diseases, Tanshinone IIA has also shown s...

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Bibliographic Details
Main Authors: Tongtong Zhang, Xinglin Chen, Xiran Ju, Jixiang Yuan, Jielong Zhou, Zhihang Zhang, Guanqun Ju, Dongliang Xu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:European Journal of Medical Research
Subjects:
Tanshinone IIA
Prostate cancer
Molecular docking
Molecular dynamics
Bioinformatics
Online Access:https://doi.org/10.1186/s40001-023-01477-w

Internet

https://doi.org/10.1186/s40001-023-01477-w

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