Ectopic overexpression of Kir6.1 in the mouse heart impacts on the life expectancy
Abstract We recently reported the reduced ATP-sensitive potassium (KATP) channel activities in the transgenic mouse heart overexpressing the vascular type KATP channel pore-forming subunit (Kir6.1). Although dysfunction of cardiac KATP channel has been nominated as a cause of cardiomyopathy in human...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2018-08-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-018-30175-5 |