Intratumoral Delivery of Doxorubicin on Folate-Conjugated Graphene Oxide by In-Situ Forming Thermo-Sensitive Hydrogel for Breast Cancer Therapy

By taking advantage of the pH-sensitive drug release property of graphene oxide (GO) after intracellular uptake, we prepared folic acid (FA)-conjugated GO (GOFA) for targeted delivery of the chemotherapeutic drug doxorubicin (DOX). GOFA-DOX was further encapsulated in an injectable in-situ forming t...

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Bibliographic Details
Main Authors: Yi Teng Fong, Chih-Hao Chen, Jyh-Ping Chen
Format: Article
Language:English
Published: MDPI AG 2017-11-01
Series:Nanomaterials
Subjects:
Online Access:https://www.mdpi.com/2079-4991/7/11/388