Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases

Small molecule inhibitors of RORγt for Th17 regulation in inflammatory and autoimmune diseases

As a ligand-dependent transcription factor, retinoid-associated orphan receptor γt (RORγt) that controls T helper (Th) 17 cell differentiation and interleukin (IL)-17 expression plays a critical role in the progression of several inflammatory and autoimmune conditions. An emerging novel approach to...

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Bibliographic Details
Main Authors: Jiuping Zeng, Mingxing Li, Qianyun Zhao, Meijuan Chen, Long Zhao, Shulin Wei, Huan Yang, Yueshui Zhao, Anqi Wang, Jing Shen, Fukuan Du, Yu Chen, Shuai Deng, Fang Wang, Zhuo Zhang, Zhi Li, Tiangang Wang, Shengpeng Wang, Zhangang Xiao, Xu Wu
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Journal of Pharmaceutical Analysis
Subjects:
T helper 17
RORγt
Small-molecule inhibitor
Inflammatory disease
Autoimmune disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2095177923000977

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http://www.sciencedirect.com/science/article/pii/S2095177923000977

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