Evaluation of whole-genome sequence to predict drug resistance of nine anti-tuberculosis drugs and characterize resistance genes in clinical rifampicin-resistant Mycobacterium tuberculosis isolates from Ningbo, China

Evaluation of whole-genome sequence to predict drug resistance of nine anti-tuberculosis drugs and characterize resistance genes in clinical rifampicin-resistant Mycobacterium tuberculosis isolates from Ningbo, China

SettingControlling drug-resistant tuberculosis in Ningbo, China.ObjectiveWhole-genome sequencing (WGS) has not been employed to comprehensively study Mycobacterium tuberculosis isolates, especially rifampicin-resistant tuberculosis, in Ningbo, China. Here, we aim to characterize genes involved in dr...

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Bibliographic Details
Main Authors: Yang Che, Yi Lin, Tianchi Yang, Tong Chen, Guoxin Sang, Qin Chen, Tianfeng He
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Public Health
Subjects:
drug resistance
drug susceptibility test
whole-genome sequencing
rifampicin-resistant tuberculosis
gene mutation
Online Access:https://www.frontiersin.org/articles/10.3389/fpubh.2022.956171/full

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https://www.frontiersin.org/articles/10.3389/fpubh.2022.956171/full

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