Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions

Bottom-up modeling approach for the quantitative estimation of parameters in pathogen-host interactions

Opportunistic fungal pathogens can cause bloodstream infection and severe sepsis upon entering the blood stream of the host. The early immune response in human blood comprises the elimination of pathogens by antimicrobial peptides and innate immune cells, such as neutrophils or monocytes. Mathematic...

Full description

Bibliographic Details
Main Authors: Teresa eLehnert, Sandra eTimme, Johannes ePollmächer, Kerstin eHünniger, Oliver eKurzai, Marc Thilo eFigge
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-06-01
Series:Frontiers in Microbiology
Subjects:
Candida albicans
agent-based model
parameter estimation
pathogen-host interaction
State-based model
whole-blood infection assay
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00608/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fmicb.2015.00608/full

Similar Items