MiRNA-494 induces trophoblast senescence by targeting SIRT1

Objective Although the mechanism underlying preeclampsia (PE) has been widely explored, the mechanisms related to senescence have not yet been fully revealed. Therefore, we investigated the role of the miR-494/longevity protein Sirtuin 1 (SIRT1) axis in PE. Methods Human placental tissue was obtaine...

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Bibliographic Details
Main Authors: Sha Su, Linlin Zhong, Shijin Huang, Lingjie Deng, Lihong Pang
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Hypertension in Pregnancy
Subjects:
Online Access:http://dx.doi.org/10.1080/10641955.2023.2219774