The Th1-Promoting Effects of Dehydroepiandrosterone Can Provide an Explanation for the Stronger Th1-Immune Response of Women

Estrogens foster immunological processes driven by CD4+ Th2 cells and B cells and androgens foster Th1 CD4+ and CD8+ cell activity. Higher levels of IFN-gamma and IL-2 and lower levels of IL-4 and IL-10 are detected in the phytohemagglutinin-stimulated lymphocyte culture supernatants of men compared...

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Bibliographic Details
Main Author: Namazi Mohammad Reza
Format: Article
Language:English
Published: Tehran University of Medical Sciences 2009-03-01
Series:Iranian Journal of Allergy, Asthma and Immunology
Online Access:https://ijaai.tums.ac.ir/index.php/ijaai/article/view/237